We are using intelligent machines for everything from self-driving cars to online searches. But how about leveraging artificial intelligence, or AI, to save lives? “A momentous change in health care is under way,” says Suchi Saria, an associate professor in computational biology at Johns Hopkins, with startups harnessing the recent explosion of electronic health data to help doctors make critical decisions and extend care to patients between appointments. Here are five ways that machine learning is poised to bring new rigor to medicine.